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IPO7 抗体 (AA 365-460) (Biotin)

This anti-IPO7 antibody (ABIN1399909) is a Rabbit Polyclonal antibody detecting IPO7 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
产品编号 ABIN1399909
发货至: 中国

Quick Overview for IPO7 抗体 (AA 365-460) (Biotin) (ABIN1399909)

抗原

See all IPO7 抗体
IPO7 (Importin 7 (IPO7))

适用

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宿主

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克隆类型

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多克隆

标记

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This IPO7 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 365-460

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RanBP7/Importin 7

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    IPO7 (Importin 7 (IPO7))

    别名

    RanBP7

    背景

    Synonyms: Imp 7, Imp7, Importin-7, Importin7, IPO 7, IPO7, IPO7_HUMAN, Ran binding protein 7, Ran-binding protein 7, RANBP 7, RanBP7.

    Background: Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.

    途径

    Protein targeting to Nucleus
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