HEXDC 抗体 (AA 1-100) (AbBy Fluor® 647)
Quick Overview for HEXDC 抗体 (AA 1-100) (AbBy Fluor® 647) (ABIN1398972)
抗原
See all HEXDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HEXDC
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亚型
- IgG
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anti-Hexosaminidase D (HEXDC) (AA 1-100) antibody
HEXDC 适用: 人 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase D (HEXDC) (AA 135-166) antibodyHEXDC 适用: 人 WB 宿主: 兔 Polyclonal RB55881 unconjugated
anti-Hexosaminidase D (HEXDC) (AA 1-493) antibodyHEXDC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hexosaminidase D (HEXDC) (C-Term) antibodyHEXDC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HEXDC (Hexosaminidase D (HEXDC))
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别名
- HEXDC
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背景
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Synonyms: Beta hexosaminidase D, Beta N acetylhexosaminidase, FLJ23825, Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing, hexosaminidase glycosyl hydrolase family 20, catalytic domain, Hexosaminidase D, Hexosaminidase domain containing protein, N acetyl beta galactosaminidase, HEXDC_HUMAN.
Background: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
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基因ID
- 284004
抗原
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