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FBXO15 抗体 (AA 101-200) (AbBy Fluor® 647)

This AbBy Fluor® 647-conjugated 兔 多克隆 anti-FBXO15 antibody specifically detects FBXO15 in WB, IF (cc) 和 IF (p). The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN1398846
发货至: 中国
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Quick Overview for FBXO15 抗体 (AA 101-200) (AbBy Fluor® 647) (ABIN1398846)

抗原

See all FBXO15 抗体
FBXO15 (F-Box Protein 15 (FBXO15))

适用

  • 20
  • 16
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠, 大鼠

宿主

  • 34

克隆类型

  • 34
多克隆

标记

  • 12
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FBXO15 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 29
  • 14
  • 12
  • 12
  • 9
  • 6
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    AA 101-200

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Fbx15

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FBXO15 (F-Box Protein 15 (FBXO15))

    别名

    Fbx15

    背景

    Synonyms: F box protein 15, F-box only protein 15, F-box protein 15, Fbxo15, MGC39671, FBX15_HUMAN.

    Background: FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.

    基因ID

    201456
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