RIT1 抗体 (AA 141-219) (AbBy Fluor® 647)
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北京 101111
Quick Overview for RIT1 抗体 (AA 141-219) (AbBy Fluor® 647) (ABIN1398822)
抗原
See all RIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-219
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RIT1
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亚型
- IgG
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anti-Ras-Like Without CAAX 1 (RIT1) (C-Term) antibody
RIT1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (AA 1-219) antibodyRIT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (C-Term) antibodyRIT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) antibodyRIT1 适用: 人 WB 宿主: 小鼠 Monoclonal 14G7 unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (AA 120-217) antibodyRIT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (C-Term) antibodyRIT1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (AA 108-157) antibodyRIT1 适用: 人, Cow, 兔, 绵羊, 犬, 豚鼠, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 1 (RIT1) (C-Term) antibodyRIT1 适用: 人, Cow, 兔, 绵羊, 大鼠, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RIT1 (Ras-Like Without CAAX 1 (RIT1))
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别名
- RIT1
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背景
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Synonyms: GTP binding protein Roc1, GTP-binding protein Rit1, Ras like protein expressed in many tissues, Ras like without CAAX 1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1, RIBB, Ric like expressed in many tissues, RIT, RIT1, RIT1_HUMAN, ROC1.
Background: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.Neuronal activity dramatically increases the concentration of cytosolic Ca2+, which then serves as a second messenger to direct diverse cellular responses. Calmodulin is a primary mediator of Ca2+ signals in the nervous system. Ric, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin. In addition, two Ras-like human proteins, Rin and Rit (Ric-related gene expressed in many tissues), which are 71 % and 66 % identical to RIC respectively, share related G2 domains with Ric. While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, Rit and Rin lack the recognition signal for C-terminal prenylation. Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, which provides a mechanism for membrane association. Rin binds calmodulin through a C-terminal binding motif. Rit and Ric are widely expressed, whereas expression of Rin is restricted to the neuron system. In conclusion, Rit and Rin define a novel subfamily of Ras-related proteins
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基因ID
- 6016
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途径
- Neurotrophin Signaling Pathway
抗原
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