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PANK3 抗体 (AA 271-370) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-PANK3 antibody specifically detects PANK3 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 大鼠 samples.
产品编号 ABIN1398511
发货至: 中国
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Quick Overview for PANK3 抗体 (AA 271-370) (Biotin) (ABIN1398511)

抗原

See all PANK3 抗体
PANK3 (Pantothenate Kinase 3 (PANK3))

适用

  • 24
  • 14
大鼠

宿主

  • 32
  • 6

克隆类型

  • 34
  • 4
多克隆

标记

  • 15
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PANK3 antibody is conjugated to Biotin

应用范围

  • 38
  • 19
  • 13
  • 13
  • 13
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    AA 271-370

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PANK3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PANK3 (Pantothenate Kinase 3 (PANK3))

    别名

    PANK3

    背景

    Synonyms: hPanK3, MGC16863, OTTHUMP00000160961, Pank3, PANK3_HUMAN, Pantothenate kinase 3, pantothenic acid kinase, Pantothenic acid kinase 3.

    Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4?-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.

    基因ID

    79646

    途径

    Ribonucleoside Biosynthetic Process
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