SESN1 抗体 (AA 401-492) (AbBy Fluor® 647)
Quick Overview for SESN1 抗体 (AA 401-492) (AbBy Fluor® 647) (ABIN1398426)
抗原
See all SESN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-492
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SESN1/PA26
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亚型
- IgG
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anti-Sestrin 1 (SESN1) (AA 1-551) antibody
SESN1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) antibodySESN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 224-337) antibodySESN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 271-370) antibodySESN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 1-551) antibodySESN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibodySESN1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB18601 unconjugated
anti-Sestrin 1 (SESN1) (AA 45-492) antibodySESN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 375-424) antibodySESN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (C-Term) antibodySESN1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 14-43), (N-Term) antibodySESN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB18600 unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SESN1 (Sestrin 1 (SESN1))
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别名
- PA26
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背景
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Synonyms: p53 regulated PA26 nuclear protein, p53 regulated protein PA26, p53-regulated protein PA26, PA26, sesn1, SESN1_HUMAN, SEST1, sestrin 1, Sestrin-1.
Background: Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
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基因ID
- 27244
抗原
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