DHRS7 抗体 (AA 61-160) (FITC)
Quick Overview for DHRS7 抗体 (AA 61-160) (FITC) (ABIN1398140)
抗原
See all DHRS7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-160
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预测反应
- Human,Mouse,Rat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DHRS7
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DHRS7 (Dehydrogenase/reductase (SDR Family) Member 7 (DHRS7))
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别名
- DHRS7
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背景
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Synonyms: CGI 86, CGI86, Dehydrogenase/reductase SDR family member 7, DHRS7A, retDSR4, Retinal short chain dehydrogenase/reductase 4, RETSDR4, DHRS7_HUMAN.
Background: DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
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基因ID
- 51635
抗原
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