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TROVE2 抗体 (AA 331-430) (Biotin)

This anti-TROVE2 antibody is a 兔 多克隆 antibody detecting TROVE2 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1397908
发货至: 中国

Quick Overview for TROVE2 抗体 (AA 331-430) (Biotin) (ABIN1397908)

抗原

See all TROVE2 抗体
TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TROVE2 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 331-430

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TROVE-2/SSA2

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

    别名

    TROVE-2

    背景

    Synonyms: TROVE2, 60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, 60 kDa SS A/Ro ribonucleoprotein, 60 kDa SS-A/Ro ribonucleoprotein, Autoantigen Ro/SSA, 60-KD, bA101E13.2, Gastric cancer multi drug resistance protein, Ribonucleoprotein autoantigen SS A/Ro, RO 60, Ro 60 kDa autoantigen, RO60, RO60_HUMAN, RoRNP, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, Sjogren syndrome antigen A2 60kD ribonucleoprotein autoantigen SS A/Ro, Sjogren syndrome antigen A2 60 kDa ribonucleoprotein autoantigen SS A/Ro, Sjogren syndrome antigen A2, SS A, SS-A, SS-A/Ro, SSA 2, SSA, SSA2, TROVE 2, TROVE domain family member 2, TROVE2.

    Background: Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE), neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1). Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50 % of patients with SLE and in up to 97 % of patients with Sjqgren syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2). Most anti-Ro/SSA-positive sera detect not only the main protein, but also a smaller Ro/SSA protein (2). The genes which encode the smaller and larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?). La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjren syndrome and SLE (6).

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