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GRM2 抗体 (AbBy Fluor® 647)

This anti-GRM2 antibody is a 兔 多克隆 antibody detecting GRM2 in IF (p). Suitable for 人, 大鼠, 小鼠, Cow, 犬 和 小鸡.
产品编号 ABIN1396547
发货至: 中国

Quick Overview for GRM2 抗体 (AbBy Fluor® 647) (ABIN1396547)

抗原

See all GRM2 抗体
GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

适用

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人, 大鼠, 小鼠, Cow, 犬, 小鸡

宿主

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克隆类型

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多克隆

标记

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This GRM2 antibody is conjugated to AbBy Fluor® 647

应用范围

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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    小鸡, Cow, 犬, 人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GRM2/GLUR2

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    IF(IHC-P)(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

    别名

    Metabotropic Glutamate Receptor 2

    背景

    Synonyms: Glutamate Receptor Metabotropic 2, Gprc1b, AMPA selective glutamate receptor 2, GLUR 2, GLUR2, GLURB, Glutamate receptor metabotropic 2, Metabotropic Glutamate Receptor 2, GPRC1B, GRM 2, Grm2, mGlu 2, MGlu2, MGLUR 2, Mglur2, GRM2_HUMAN.

    Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    分子量

    96kDa

    基因ID

    2912

    途径

    cAMP Metabolic Process, Dicarboxylic Acid Transport
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