Fibrillin 2 抗体 (AA 1001-1200) (AbBy Fluor® 647)
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北京 101111
Quick Overview for Fibrillin 2 抗体 (AA 1001-1200) (AbBy Fluor® 647) (ABIN1395540)
抗原
See all Fibrillin 2 (FBN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1200
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Fibrillin 2
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亚型
- IgG
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anti-Fibrillin 2 (FBN2) (AA 1550-1791) antibody
FBN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 2 (FBN2) (AA 304-484) antibodyFBN2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 2 (FBN2) (AA 2776-2876) antibodyFBN2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1C2 unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Fibrillin 2 (FBN2)
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别名
- Fibrillin 2
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背景
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Synonyms: CCA, congenital contractural arachnodactyly Marfanoid-like, DA9, FBN2, FBN2_HUMAN, fibrillin 2 congenital contractural arachnodactyly, Fibrillin-2.
Background: Extracellular glycoproteins fibrillin-1 and -2 are major components of connective tissue microfibrils. Fibrillin-2 containing microfibrils regulate the early process of elastic fiber assembly in tissue. Mutations in the fibrillin-2 gene resulting in impaired assembly of fibrillin-2 may lead to molecular congenital contractural arachnodactyly. Fibrillin-2 constitutes the backbone of microfibrils which insert directly into the lamina densa of basement membranes. Epithelial cells primarily deposit fibrillin into the extracellular matrix in a nonfibrillar form. Mutations in the 8-cysteine motif of Fibrillin-2 alters its binding to microfibril-associated glycoprotein-1 (MAGP-1), which may increase the severity of congenital contractural arachnodactyly.
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途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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