STRN3 抗体 (AA 75-180) (Biotin)
Quick Overview for STRN3 抗体 (AA 75-180) (Biotin) (ABIN1395367)
抗原
See all STRN3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 75-180
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Striatin 3
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- STRN3 (Striatin, Calmodulin Binding Protein 3 (STRN3))
-
别名
- Striatin 3/SG2NA
-
背景
-
Synonyms: Striatin3, Striatin-3, Cell cycle autoantigen SG2NA, Cell cycle S/G2 nuclear autoantigen, GS2NA, nuclear autoantigen, S/G2 antigen, SG2NA, Striatin 3, Striatin, calmodulin binding protein 3, STRN3_HUMAN.
Background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
-