GARP 抗体 (AA 856-960) (FITC)
Quick Overview for GARP 抗体 (AA 856-960) (FITC) (ABIN1395122)
抗原
See all GARP (CNGB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 856-960
-
预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CNGB1
-
亚型
- IgG
-
-
anti-Cyclic Nucleotide Gated Channel beta 1 (CNGB1) (AA 131-253) antibody
CNGB1 适用: 人 ELISA, WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclic Nucleotide Gated Channel beta 1 (CNGB1) (Internal Region) antibodyCNGB1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclic Nucleotide Gated Channel beta 1 (CNGB1) (Internal Region) antibodyCNGB1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))
-
别名
- CNG4/GARP
-
背景
-
Synonyms: CNCG2, CNCG3L, CNCG4, CNG 4, CNG-4, CNG channel 4, CNG channel beta 1, CNG4, CNGB 1, CNGB1, CNGB1B, Cyclic nucleotide gated cation channel 4, Cyclic nucleotide gated cation channel, Cyclic nucleotide gated cation channel beta 1, Cyclic nucleotide gated cation channel gamma, Cyclic nucleotide gated cation channel modulatory subunit, Cyclic nucleotide gated channel photoreceptor cGMP gated 3 gamma like, Cyclic nucleotide gated channel beta 1, GAR1, Glutamic acid rich protein, RCNC2, RCNCb, RCNCbeta, RP45, CNGB1_HUMAN.
Background: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).
-
UniProt
- Q14028
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
-
