GDE1 抗体 (AA 231-331) (Biotin)
Quick Overview for GDE1 抗体 (AA 231-331) (Biotin) (ABIN1394809)
抗原
See all GDE1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 231-331
- 
                                            交叉反应
- 小鼠
- 
                                            预测反应
- Human,Rat,Dog,Pig,Horse,Rabbit
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human MIR16/GDE1
- 
                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 IHC-P 1:200-400
 IHC-F 1:100-500
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C for 12 months.
- 
                                            有效期
- 12 months
 
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    - GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
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                                            别名
- MIR16/GDE1
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                                            背景
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                        Synonyms: EC 3.1.4.44, GDE1, Glycerophosphodiester phosphodiesterase 1, Membrane interacting protein of RGS16, RGS16 interacting membrane protein, GDE1_HUMAN. Background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. 
 抗原
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