NTSR2 抗体 (AA 151-250) (AbBy Fluor® 555)
Quick Overview for NTSR2 抗体 (AA 151-250) (AbBy Fluor® 555) (ABIN1394597)
抗原
See all NTSR2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 151-250
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                                            交叉反应
- 小鼠
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                                            预测反应
- Human,Rat,Dog,Cow,Sheep,Rabbit
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2
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                                            亚型
- IgG
 
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                                            应用备注
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                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - NTSR2 (Neurotensin Receptor 2 (NTSR2))
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                                            别名
- Neurotensin Receptor 2
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                                            背景
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                        Synonyms: Levocabastine sensitive neurotensin receptor, Levocabastine-sensitive neurotensin receptor, Neurotensin receptor type 2, NT R 2, NT-R-2, NTR2, NTR2 receptor, NTR2_HUMAN, Ntsr2. Background: Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner. 
 抗原
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