DDAH1 抗体 (AA 201-285) (FITC)
Quick Overview for DDAH1 抗体 (AA 201-285) (FITC) (ABIN1394558)
抗原
See all DDAH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-285
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DDAH1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DDAH1 (Dimethylarginine Dimethylaminohydrolase 1 (DDAH1))
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别名
- DDAH1
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背景
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Synonyms: DDAH, DDAH I, DDAH-1, DDAH1, DDAH1_HUMAN, DDAHI, Dimethylargininase 1, Dimethylargininase-1, Dimethylarginine dimethylaminohydrolase 1, NG, NG-dimethylarginine dimethylaminohydrolase 1, NG NG dimethylarginine dimethylaminohydrolase.
Background: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
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基因ID
- 23576
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UniProt
- O94760
抗原
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