CACNA1G/CACNA1H (AA 311-420) 抗体 (AbBy Fluor® 555)
Quick Overview for CACNA1G/CACNA1H (AA 311-420) 抗体 (AbBy Fluor® 555) (ABIN1394477)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-420
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from CACNA1G + CACNA1H
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CACNA1G/CACNA1H
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别名
- CACNA1G + CACNA1H
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背景
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Synonyms: Cav3.1c, Low voltage activated calcium channel alpha1 3.2 subunit, NBR13, Voltage dependent T type calcium channel subunit alpha 1G, Voltage dependent T type calcium channel subunit alpha 1H, Voltage gated calcium channel subunit alpha Cav3.1, Voltage gated calcium channel subunit alpha Cav3.2, CAC1G_HUMAN, CAC1H_HUMAN.
Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. There are 2 isoforms of CACNA1H and 14 isoforms if CACNA1G, produced by alternative splicing.
抗原
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