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SLC5A3 抗体 (AA 251-350) (Biotin)

SLC5A3 适用: 人 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1394299
发货至: 中国
  • 抗原 See all SLC5A3 抗体
    SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))
    抗原表位
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 251-350
    适用
    • 42
    • 14
    • 8
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 38
    • 3
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A3 antibody is conjugated to Biotin
    应用范围
    • 13
    • 13
    • 13
    • 12
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLC5A3/SMIT
    亚型
    IgG
    Top Product
    Discover our top product SLC5A3 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))
    别名
    SLC5A3/SMIT (SLC5A3 产品)
    别名
    AA623876 antibody, BF642829 antibody, Smit1 antibody, SMIT antibody, SMIT1 antibody, SMIT2 antibody, Smit antibody, solute carrier family 5 (inositol transporters), member 3 antibody, solute carrier family 5 member 3 antibody, Slc5a3 antibody, SLC5A3 antibody
    背景

    Synonyms: Na+/myo inositol cotransporter, Na+/myo-inositol cotransporter, SC5A3_HUMAN, SLC5A3, SMIT, SMIT2, sodium/myo inositol cotransporter 1, Sodium/myo inositol cotransporter, Sodium/myo-inositol cotransporter, solute carrier family 5 inositol transporters, member 3, Solute carrier family 5 member 3.

    Background: Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol, it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.

    途径
    Inositol Metabolic Process
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