NOTUM 抗体 (AA 351-450) (FITC)
Quick Overview for NOTUM 抗体 (AA 351-450) (FITC) (ABIN1394018)
抗原
See all NOTUM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-450
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预测反应
- Human,Mouse,Rat,Dog,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NOTUM
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亚型
- IgG
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anti-Notum Pectinacetylesterase Homolog (NOTUM) (AA 100-235) antibody
NOTUM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Notum Pectinacetylesterase Homolog (NOTUM) (AA 20-320) antibodyNOTUM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Notum Pectinacetylesterase Homolog (NOTUM) (N-Term) antibodyNOTUM 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NOTUM (Notum Pectinacetylesterase Homolog (NOTUM))
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别名
- NOTUM
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背景
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Synonyms: NOTUM, notum pectinacetylesterase homolog Drosophila, Notum pectinacetylesterase homolog, NOTUM_HUMAN.
Background: Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans. The gene that encodes Notum consists of approximately 9,334 bases and maps to human chromosome 17q25.3. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.
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基因ID
- 147111
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UniProt
- Q6P988
抗原
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