KIRREL3 抗体 (AA 351-450) (Biotin)
Quick Overview for KIRREL3 抗体 (AA 351-450) (Biotin) (ABIN1393777)
抗原
See all KIRREL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-450
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KIRREL3
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- KIRREL3 (Kin of IRRE Like 3 (KIRREL3))
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别名
- KIRREL3
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背景
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Synonyms: Kin of IRRE like 3 Drosophila, Kin of IRRE like 3, Kin of irregular chiasm like protein 3 , KIRRE, KIRREL 3, KIRREL-3, MRD4, NEPH2, Nephrin like 2, PRO19814, PRO4502, yUNQ5923, KIRR3_HUMAN.
Background: NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).
抗原
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