ARHGEF25/GEFT 抗体 (AA 251-340) (Biotin)
Quick Overview for ARHGEF25/GEFT 抗体 (AA 251-340) (Biotin) (ABIN1393663)
抗原
See all ARHGEF25/GEFT (ARHGEF25) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-340
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GEFT
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亚型
- IgG
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anti-Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25) (Internal Region) antibody
ARHGEF25 适用: 大鼠, 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25) (AA 226-446) antibodyARHGEF25 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25) (AA 506-555) antibodyARHGEF25 适用: 大鼠, 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25) (C-Term) antibodyARHGEF25 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))
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别名
- GEFT
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背景
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Synonyms: ARHGEF25, ARHGP_HUMAN, GEFT, p63RhoGEF, Guanine nucleotide exchange factor GEFT, p63RhoGEF , RAC/CDC42 exchange factor, Rac/Cdc42/Rho exchange factor GEFT, Rho guanine nucleotide exchange factor 25, RhoA/RAC/CDC42 exchange factor, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT.
Background: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
抗原
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