NERP-1 抗体 (AA 231-330) (Biotin)
Quick Overview for NERP-1 抗体 (AA 231-330) (Biotin) (ABIN1393369)
抗原
See all NERP-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-330
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交叉反应
- 小鼠, 大鼠, 斑马鱼
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预测反应
- Human,Cow,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NERP1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))
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别名
- VGF/NERP-1
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背景
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Synonyms: Nerve growth factor inducible, Neurosecretory protein VGF, VGF, VGF_HUMAN, SCG7, SgVII, Neuroendocrine regulatory peptide-1, NERP-1, NERP1
Background: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
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基因ID
- 7425
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UniProt
- O15240
抗原
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