GPR143 抗体 (AA 201-300) (Biotin)
Quick Overview for GPR143 抗体 (AA 201-300) (Biotin) (ABIN1393345)
抗原
See all GPR143 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human OA1
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亚型
- IgG
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anti-G Protein-Coupled Receptor 143 (GPR143) (AA 1-424) antibody
GPR143 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 143 (GPR143) (AA 314-404) antibodyGPR143 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- GPR143 (G Protein-Coupled Receptor 143 (GPR143))
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别名
- OA1/GPR143
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背景
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Synonyms: ALBINISM OCULAR TYPE I, G protein coupled receptor 143, G-protein coupled receptor 143, GP143_HUMAN, GPR143, MOA1, NETTLESHIP FALLS TYPE OCULAR ALBINISM, Ocular albinism type 1 protein, Ocular albinism type 1 protein homolog, Ocular albinism1 Nettleship Falls type.
Background: G protein-coupled receptors (GPRs or GPCRs), are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR143, also designated ocular albinism type 1 protein (OA1), is detected exclusively in pigment cells. OA1, which is a multi-pass membrane protein, is a melanosomal protein expressed primarily in pigment cells. Defects in the gene encoding for OA1 cause ocular albinism, an X-linked disorder mainly characterized by retinal hypopigmentation and visual impairment.
抗原
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