SPG21 抗体 (AA 151-250) (Biotin)
Quick Overview for SPG21 抗体 (AA 151-250) (Biotin) (ABIN1393309)
抗原
See all SPG21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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预测反应
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SPG21
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亚型
- IgG
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anti-Spastic Paraplegia 21 (SPG21) (AA 1-308) antibody
SPG21 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Paraplegia 21 (SPG21) (AA 211-306) antibodySPG21 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spastic Paraplegia 21 (SPG21) (AA 211-306) antibodySPG21 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- SPG21 (Spastic Paraplegia 21 (SPG21))
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别名
- SPG21
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背景
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Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.
Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.
抗原
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