ATL1 抗体 (AA 201-300) (AbBy Fluor® 488)
Quick Overview for ATL1 抗体 (AA 201-300) (AbBy Fluor® 488) (ABIN1393150)
抗原
See all ATL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SPG3A/Atlastin
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亚型
- IgG
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anti-Atlastin GTPase 1 (ATL1) (AA 1-100) antibody
ATL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Atlastin GTPase 1 (ATL1) (N-Term) antibodyATL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 1-100) antibodyATL1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1F6B12 unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 1-280) antibodyATL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 220-350) antibodyATL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) antibodyATL1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ATL1 (Atlastin GTPase 1 (ATL1))
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别名
- SPG3A/Atlastin
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背景
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Synonyms: AD FSP, atl1, ATLA1_HUMAN, Atlastin GTPase 1, Atlastin-1, Atlastin1, Brain specic GTP binding protein, Brain-specic GTP-binding protein, FSP1, GBP-3, GBP3, GTP-binding protein 3, Guanine nucleotide-binding protein 3, Guanylate binding protein 3, hGBP3, HSN1D, Spastic paraplegia 3 protein A, SPG 3A, SPG3, SPG3A.
Background: Atlastins are Golgi-localized, integral membrane proteins that function as GTPases. The Atlastin proteins, also designated SPG3A and guanylate-binding protein 3, comprise a Dynamin superfamily that plays a role in axonal maintenance. Hereditary spastic paraplegia (HSP) is an inherited neurodegenerative disorder that is characterized by retrograde axonal degeneration. HSP primarily affects long corticospinal neurons and causes spastic lower extremity weakness. Spastin, a microtubule (MT)-severing AAA ATPase, is a binding partner of Atlastin that is involved in membrane dynamics. This Spastin/Atlastin binding may be involved in the biochemical pathway that leads to HSP development. Mutations in the Atlastin gene (SPG3A) account for approximately 10 % of all autosomal dominant HSPs, while mutations in the Spastin gene (SPG4) account for almost 40 %.
抗原
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