SH3PXD2A 抗体 (AA 261-360) (FITC)
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北京 101111
Quick Overview for SH3PXD2A 抗体 (AA 261-360) (FITC) (ABIN1392500)
抗原
See all SH3PXD2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-360
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交叉反应
- 大鼠
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预测反应
- Human,Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FISH
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亚型
- IgG
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anti-SH3 and PX Domains 2A (SH3PXD2A) antibody
SH3PXD2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (N-Term) antibodySH3PXD2A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (AA 1-1105) antibodySH3PXD2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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别名
- FISH
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背景
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Synonyms: Adapter protein TKS5, Five SH3 domain-containing protein, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Sh3md1, Sh3pxd2a, SPD2A_HUMAN, TKs5, Tyrosine kinase substrate with five SH3 domains.
Background: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo, catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).
抗原
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