Calsyntenin 1 抗体 (AA 501-600) (FITC)
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北京 101111
Quick Overview for Calsyntenin 1 抗体 (AA 501-600) (FITC) (ABIN1392494)
抗原
See all Calsyntenin 1 (CLSTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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预测反应
- Human,Mouse,Rat,Dog,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Calsyntenin 1
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亚型
- IgG
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anti-Calsyntenin 1 (CLSTN1) antibody
KD Validated CLSTN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3725 unconjugated Recombinant Antibody
anti-Calsyntenin 1 (CLSTN1) (C-Term) antibodyCLSTN1 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 35-84) antibodyCLSTN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 1-971) antibodyCLSTN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) antibodyKD Validated CLSTN1 适用: 人, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Calsyntenin 1 (CLSTN1)
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别名
- CLSTN1/Calsyntenin 1
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背景
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Synonyms: Alc alpha, Alc-alpha, Alcadein alpha 1, Alcadein alpha, Alcadein-alpha, alcalpha1, alcalpha2, Alzheimer related cadherin like protein, Alzheimer-related cadherin-like protein, Calsyntenin-1, Calsyntenin1, CLSTN 1, Clstn1, CS1, CSTN1, CSTN1_HUMAN, CTF1-alpha, FLJ32258, KIAA0911, Non classical cadherin XB31alpha, Non-classical cadherin XB31alpha, PIK3CD, SAlc-alpha, XB31alpha.
Background: Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer?s disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.
抗原
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