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TSKU 抗体 (AA 231-300) (AbBy Fluor® 488)

This anti-TSKU antibody is a 兔 多克隆 antibody detecting TSKU in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1392274
发货至: 中国

Quick Overview for TSKU 抗体 (AA 231-300) (AbBy Fluor® 488) (ABIN1392274)

抗原

See all TSKU 抗体
TSKU (Tsukushin (TSKU))

适用

  • 23
  • 2

宿主

  • 21
  • 3

克隆类型

  • 24
多克隆

标记

  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TSKU antibody is conjugated to AbBy Fluor® 488

应用范围

  • 12
  • 12
  • 8
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 231-300

    预测反应

    Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Tsukushin/LRRC54

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TSKU (Tsukushin (TSKU))

    别名

    TSK/Tsukushin/LRRC54

    背景

    Synonyms: E2 induced gene 4 protein, E2IG4, Leucine rich repeat containing protein 54, LRRC54, TSK, Tsukushi, TSK_HUMAN, TSKU.

    Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    基因ID

    25987

    UniProt

    Q8WUA8
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