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DUSP6 抗体 (FITC)

This anti-DUSP6 antibody is a 兔 多克隆 antibody detecting DUSP6 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1391912
发货至: 中国

Quick Overview for DUSP6 抗体 (FITC) (ABIN1391912)

抗原

See all DUSP6 抗体
DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

适用

  • 95
  • 58
  • 51
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 82
  • 12
  • 2
  • 1

克隆类型

  • 76
  • 21
多克隆

标记

  • 46
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP6 antibody is conjugated to FITC

应用范围

  • 63
  • 32
  • 19
  • 17
  • 10
  • 10
  • 9
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DUSP6

    亚型

    IgG
  • 应用备注

    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Li, Zhou, Ying, Shi, Cheng, Ren, Griffin, Jia, Li, Moorman, Yao: "Hepatitis C virus-induced reduction in miR-181a impairs CD4(+) T-cell responses through overexpression of DUSP6." in: Hepatology (Baltimore, Md.), (2015) (PubMed).

  • 抗原

    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

    别名

    Dusp6/Mkp-3

    背景

    Synonyms: Dual specicity phosphatase 6, Dual specicity phosphatase 6 isoform a, Dual specicity protein phosphatase 6, Dual specicity protein phosphatase PYST1, DUS6_HUMAN, DUSP 6, DUSP 6a, Dusp6, DUSP6a, MAP kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, Mitogen-activated protein kinase phosphatase 3, MKP 3, MKP-3, MKP3, PYST 1, PYST1, Serine/threonine specic protein phosphatase.

    Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.

    基因ID

    8642

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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