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ATRNL1 抗体 (AA 501-600) (Biotin)

ATRNL1 适用: 人 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1391659
发货至: 中国
  • 抗原 See all ATRNL1 抗体
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    抗原表位
    • 14
    • 1
    AA 501-600
    适用
    • 17
    • 2
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATRNL1 antibody is conjugated to Biotin
    应用范围
    • 13
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ATRNL1
    亚型
    IgG
    Top Product
    Discover our top product ATRNL1 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    别名
    ATRNL1 (ATRNL1 产品)
    别名
    AI504415 antibody, AW555641 antibody, Alp antibody, Atrnl antibody, Atrnlp antibody, RGD1563485 antibody, ALP antibody, bA338L11.1 antibody, bA454H24.1 antibody, attractin like 1 antibody, ATRNL1 antibody, Atrnl1 antibody
    背景

    Synonyms: ATRN1_HUMAN, ATRNL1, Attractin-like protein 1, KIAA0534.

    Background: ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus.

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