NAV1 抗体 (AA 1426-1475) (AbBy Fluor® 555)
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北京 101111
Quick Overview for NAV1 抗体 (AA 1426-1475) (AbBy Fluor® 555) (ABIN1391441)
抗原
See all NAV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1426-1475
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预测反应
- Human,Mouse,Rat,Dog,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Neuron navigator 1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NAV1 (Neuron Navigator 1 (NAV1))
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别名
- Neuron navigator 1
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背景
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Synonyms: Nav 1, Nav1, POMFIL 3, POMFIL3, Pore membrane and/or filament interacting like protein 3, Protein Steerin 1, Protein Steerin1, Steerin 1, Steerin1, unc-53 homolog 1, DKFZp781D0314, FLJ12560, FLJ14203, mNav1, NAV1_HUMAN.
Background: Neuron navigator 1 is a 1877 amino acid cytoplasmic protein that is involved in neuronal migration. Neuron navigtor 1 is widely expressed at low levels, though highest expression is found in both adult and fetal nervous tissue. Through interaction with tubulin, Neuron navigator 1 associates with a subset of mirotubule plus ends present in the growth cone. Overexpression of Neuron navigator 1 leads to microtubule bundling, whereas a reduction of its levels causes loss of directionality in the migration of pontine cell leading processes. There are seven isoforms of Neuron navigator 1 that are produced as a result of alternative splicing events.
抗原
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