ABLIM1 抗体 (AA 681-778) (AbBy Fluor® 488)
Quick Overview for ABLIM1 抗体 (AA 681-778) (AbBy Fluor® 488) (ABIN1391338)
抗原
See all ABLIM1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 681-778
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                                            预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human ABLIM1
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                                            亚型
- IgG
 
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                                            应用备注
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                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
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                                            别名
- ABLIM1
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                                            背景
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                        Synonyms: ABLIM 1, ABLIM, abLIM-1, ABLIM-L, ABLIM-M, ABLIM-S, ABLIM1, ABLM1_HUMAN, Actin binding double zinc finger protein, Actin binding LIM protein 1, Actin binding LIM protein family member 1, Actin-binding double zinc finger protein, Actin-binding double zinc finger protein, Actin-binding LIM protein 1, Actin-binding LIM protein family member 1, DKFZp781D0148, FLJ14564, KIAA0059, LIM actin binding protein 1, LIMAB 1, LIMAB1, Limatin, RGD1565768, RP11-317F20.1. Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription. 
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                                            基因ID
- 3983
 抗原
- 
                    
 
                                     
                                     
                                    