Synaptojanin 2 抗体 (AA 401-500) (FITC)
Quick Overview for Synaptojanin 2 抗体 (AA 401-500) (FITC) (ABIN1390916)
抗原
See all Synaptojanin 2 (SYNJ2) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 401-500
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                                            预测反应
- Human,Mouse,Rat
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human Synaptojanin 2
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                                            亚型
- IgG
 
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                                            应用备注
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                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - Synaptojanin 2 (SYNJ2)
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                                            别名
- Synaptojanin 2
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                                            背景
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                        Synonyms: 5-trisphosphate 5-phosphatase 2, Inositol phosphate 5' phosphatase 2, INPP 5H, INPP5H, KIAA0348, MGC44422, SJ2, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, SYNJ 2, Synj2, SYNJ2_HUMAN. Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton. 
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                                            基因ID
- 8871
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                                            途径
- Inositol Metabolic Process
 抗原
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