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Synaptojanin 2 抗体 (AA 401-500) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-Synaptojanin 2 antibody specifically detects Synaptojanin 2 in WB, ELISA, IHC (fro) 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN1390915
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Synaptojanin 2 抗体 (AA 401-500) (Biotin) (ABIN1390915)

抗原

See all Synaptojanin 2 (SYNJ2) 抗体
Synaptojanin 2 (SYNJ2)

适用

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宿主

  • 30
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克隆类型

  • 30
  • 4
多克隆

标记

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This Synaptojanin 2 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
    • 7
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    AA 401-500

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Synaptojanin 2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Synaptojanin 2 (SYNJ2)

    别名

    Synaptojanin 2

    背景

    Synonyms: 5-trisphosphate 5-phosphatase 2, Inositol phosphate 5' phosphatase 2, INPP 5H, INPP5H, KIAA0348, MGC44422, SJ2, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, SYNJ 2, Synj2, SYNJ2_HUMAN.

    Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

    基因ID

    8871

    途径

    Inositol Metabolic Process
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