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SV2C 抗体 (AA 451-550) (Biotin)

This anti-SV2C antibody (ABIN1390849) is a Rabbit Polyclonal antibody detecting SV2C in ELISA, IHC (p), IHC (fro). Suitable for Human.
产品编号 ABIN1390849
发货至: 中国

Quick Overview for SV2C 抗体 (AA 451-550) (Biotin) (ABIN1390849)

抗原

See all SV2C 抗体
SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

适用

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宿主

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克隆类型

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多克隆

标记

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This SV2C antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 451-550

    预测反应

    Human,Mouse,Rat,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SV2C

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

    别名

    SV2C

    背景

    Synonyms: Synaptic vesicle protein 2c, SV2C_HUMAN.

    Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

    基因ID

    22987
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