Hippocalcin 抗体 (AA 101-193) (AbBy Fluor® 488)
Quick Overview for Hippocalcin 抗体 (AA 101-193) (AbBy Fluor® 488) (ABIN1390738)
抗原
See all Hippocalcin (HPCA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-193
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Hippocalcin
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亚型
- IgG
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anti-Hippocalcin (HPCA) (AA 1-193) antibody
HPCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hippocalcin (HPCA) (N-Term) antibodyHPCA 适用: 小鼠, 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hippocalcin (HPCA) antibodyHPCA 适用: 小鼠, 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hippocalcin (HPCA) antibodyHPCA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Hippocalcin (HPCA)
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别名
- Hippocalcin
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背景
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Synonyms: BDR 2, BDR2, Calcium binding protein BDR 2, Calcium binding protein BDR2, Calcium-binding protein BDR-2, Hpca, HPCA_HUMAN, Neuron specic calcium binding protein hippocalcin, Neuron specic calcium-binding protein hippocalcin, Neuron-specic calcium-binding protein hippocalcin,P23K.
Background: Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
抗原
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