NOVA1 抗体 (AA 411-510) (Biotin)
Quick Overview for NOVA1 抗体 (AA 411-510) (Biotin) (ABIN1390597)
抗原
See all NOVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 411-510
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NOVA1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))
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别名
- Nova1
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背景
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Synonyms: Neuro oncological ventral antigen 1, Neuro-oncological ventral antigen 1, NOVA 1, Nova-1, Nova1, NOVA1_HUMAN, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA binding protein Nova 1, RNA-binding protein Nova-1, Ventral neuron specic protein 1, Ventral neuron-specic protein 1.
Background: Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).
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UniProt
- P51513
抗原
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