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ISL2 抗体 (AA 201-300) (AbBy Fluor® 555)

This anti-ISL2 antibody is a 兔 多克隆 antibody detecting ISL2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1390577
发货至: 中国

Quick Overview for ISL2 抗体 (AA 201-300) (AbBy Fluor® 555) (ABIN1390577)

抗原

See all ISL2 抗体
ISL2 (ISL LIM Homeobox 2 (ISL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ISL2 antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 201-300

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Islet 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ISL2 (ISL LIM Homeobox 2 (ISL2))

    别名

    Islet 2

    背景

    Synonyms: Insulin gene enhancer protein ISL 2, Insulin gene enhancer protein ISL-2, Insulin gene enhancer protein ISL2, ISL 2, ISL 2 transcription factor, ISL 2 transcription factor LIM/homeodomain, ISL2, ISL2 transcription factor, ISL2 transcription factor LIM/homeodomain, ISL2_HUMAN, Islet-2, Islet2, FLJ10160.

    Background: Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2. Islet-2 is a nuclear protein that contains two N-terminal LIM domains, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus. Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways. Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates. Somatic, but not visceral, motor neurons maintain Islet-2 expression at later embryonic stages. An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character. Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character.

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