Endothelin 2 抗体 (AA 49-59) (AbBy Fluor® 488)
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Quick Overview for Endothelin 2 抗体 (AA 49-59) (AbBy Fluor® 488) (ABIN1390330)
抗原
See all Endothelin 2 (EDN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 49-59
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交叉反应
- Cat
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预测反应
- Human,Mouse,Rat,Dog,Cow,Cat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Endolin 2
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亚型
- IgG
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anti-Endothelin 2 (EDN2) antibody
EDN2 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) (AA 1-178) antibodyEDN2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3B4-1C5 unconjugated
anti-Endothelin 2 (EDN2) (AA 1-178) antibodyEDN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) (N-Term) antibodyEDN2 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) antibodyEDN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) (N-Term) antibodyEDN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) (AA 32-178) antibodyEDN2 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 2 (EDN2) (AA 107-136), (C-Term) antibodyEDN2 适用: 人 WB 宿主: 兔 Polyclonal RB33908 unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Endothelin 2 (EDN2)
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别名
- ET-2/Endothelin 2
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背景
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Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.
Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).
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途径
- Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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