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CCT2 抗体 (AA 131-230) (Biotin)

CCT2 适用: 人, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1390255
发货至: 中国
  • 抗原 See all CCT2 抗体
    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))
    抗原表位
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    适用
    • 49
    • 41
    • 23
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 7
    • 2
    克隆类型
    • 39
    • 11
    多克隆
    标记
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCT2 antibody is conjugated to Biotin
    应用范围
    • 43
    • 13
    • 13
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta
    亚型
    IgG
    Top Product
    Discover our top product CCT2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))
    别名
    CCT2/TCP1 beta (CCT2 产品)
    别名
    fa26a01 antibody, fc58a11 antibody, CHUNP6883 antibody, wu:fa26a01 antibody, wu:fc58a11 antibody, cct2 antibody, MGC89448 antibody, CCT2 antibody, 99D8.1 antibody, CCT-beta antibody, CCTB antibody, PRO1633 antibody, TCP-1-beta antibody, Cctb antibody, chaperonin containing TCP1 subunit 2 antibody, chaperonin containing TCP1, subunit 2 (beta) antibody, chaperonin containing Tcp1, subunit 2 (beta) antibody, T-complex protein 1 subunit beta antibody, CCT2 antibody, cct2 antibody, Cct2 antibody, cct-2 antibody
    背景

    Synonyms: CCT 2, CCT beta, CCT-beta, CCT-2, CCTB, Chaperonin containing t complex polypeptide 1 beta subunit, Chaperonin containing t complex polypeptide 1 subunit 2, Chaperonin containing TCP1 subunit 2, Chaperonin containing TCP1 subunit 2 beta, CTP:phosphocholine cytidylyltransferase 2, MGC142074, MGC142076, MGC94480, PRO1633, T complex protein 1 beta subunit, T complex protein 1 subunit beta, T-complex protein 1 subunit beta, TCP 1 beta, TCP-1-beta, TCPB_HUMAN, 99D8.1.

    Background: CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15 % of newly synthesized eukaryotic proteins (2). CCT2 is the _-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.

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