NLGN1/NLGN2 (AA 251-350) 抗体 (Biotin)
Quick Overview for NLGN1/NLGN2 (AA 251-350) 抗体 (Biotin) (ABIN1389259)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-350
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NLGN2
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亚型
- IgG
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anti-NLGN1/NLGN2 (AA 251-350) antibody
适用: 人 FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- NLGN1/NLGN2
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背景
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Synonyms: NL1, NL2, Neuroligin 1, Neuroligin 2, Neuroligin I, Ortholog of human and rat neuroligin 2 NLGN2, NLGN2_HUMAN.
Background: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
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基因ID
- 57555
抗原
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