HUNK 抗体 (AA 71-115)
Quick Overview for HUNK 抗体 (AA 71-115) (ABIN1387914)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-115
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V
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亚型
- IgG
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anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (Kinase Domain) antibody
HUNK 适用: 人, 小鼠, 大鼠, 猴, Cow, 小鸡, 犬, Hamster, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (Internal Region) antibodyHUNK 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (C-Term) antibodyHUNK 适用: 人, 猴, Cow ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (Internal Region) antibodyHUNK 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 659-690), (C-Term) antibodyHUNK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1268 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))
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别名
- Serine/threonine-protein kinase MAK-V
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背景
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Synonyms: B19, Hormonally up-regulated neu tumor-associated kinase, Hormonally upregulated neu associated, Hormonally upregulated neu associated kinase, Hormonally upregulated neu tumor associated kinase, HUNK, HUNK_HUMAN, MAKV, Serine/threonine-protein kinase MAK-V.
Background: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter- and CAB39.
抗原
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