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HUNK 抗体 (AA 71-115)

This 兔 多克隆 anti-HUNK antibody specifically detects HUNK in WB, ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN1387914
发货至: 中国
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Quick Overview for HUNK 抗体 (AA 71-115) (ABIN1387914)

抗原

HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

适用

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宿主

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克隆类型

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多克隆

标记

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This HUNK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 71-115

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

    别名

    Serine/threonine-protein kinase MAK-V

    背景

    Synonyms: B19, Hormonally up-regulated neu tumor-associated kinase, Hormonally upregulated neu associated, Hormonally upregulated neu associated kinase, Hormonally upregulated neu tumor associated kinase, HUNK, HUNK_HUMAN, MAKV, Serine/threonine-protein kinase MAK-V.

    Background: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter- and CAB39.

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