SYNM 抗体 (AA 501-650)
Quick Overview for SYNM 抗体 (AA 501-650) (ABIN1387897)
抗原
See all SYNM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-650
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Desmuslin
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." in: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).
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: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." in: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).
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- SYNM (Synemin, Intermediate Filament Protein (SYNM))
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别名
- Desmuslin
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背景
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Synonyms: DMN, SYN, Synemin, Desmuslin, SYNM, KIAA0353
Background: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
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基因ID
- 23336
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UniProt
- O15061
抗原
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