FEZ2 抗体 (AA 165-240)
Quick Overview for FEZ2 抗体 (AA 165-240) (ABIN1387871)
抗原
See all FEZ2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 165-240
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FEZ2/Zygin2
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亚型
- IgG
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anti-Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2) (AA 1-375) antibody
FEZ2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2) (C-Term) antibodyFEZ2 适用: 大鼠, 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2) (AA 264-313) antibodyFEZ2 适用: 人, Cow, 犬, Pig, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2) (C-Term) antibodyFEZ2 适用: 大鼠, 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
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别名
- FEZ2/Zygin2
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背景
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Synonyms: Fasciculation and elongation protein zeta 2, Fasciculation and elongation protein zeta-2 , FEZ 2, Fez2, FEZ2_HUMAN, Highly similar to zyginII, HUM3CL, MGC117372, Pre T/NK cell associated protein, Zygin 2, Zygin II, Zygin-2.
Background: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.
抗原
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