GBA 抗体
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北京 101111
Quick Overview for GBA 抗体 (ABIN1387836)
抗原
See all GBA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GBA Polyclonal Antibody
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交叉反应
- 人
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预测反应
- Mouse,Rat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GBA
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亚型
- IgG
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应用备注
- WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GBA (Glucosidase, Beta, Acid (GBA))
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别名
- GBA/Acid beta-Glucosidase
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背景
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Synonyms: Glucosidase beta, Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase (alt.), Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid (includes glucosylceramidase), Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.
Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
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基因ID
- 2629
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UniProt
- P04062
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途径
- Cellular Glucan Metabolic Process
抗原
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