ANT1+ANT2+ANT3+ANT4 抗体
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- 抗原
- ANT1+ANT2+ANT3+ANT4
- 适用
- 小鼠, 大鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
- 应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ANT1/2/3/4
- 亚型
- IgG
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anti-ANT1+ANT2+ANT3+ANT4 (C-Term) antibody
适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ANT1+ANT2+ANT3+ANT4 antibody适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ANT1+ANT2+ANT3+ANT4
- 背景
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Synonyms: ATP carrier protein 1, ADP ATP carrier protein heart/skeletal muscle isoform T1, ADP/ATP translocase 1, ADT1_HUMAN, ANT 1, ANT, ANT1, ATP carrier protein 2, ADP ATP carrier protein heart/skeletal muscle isoform T2, ADP/ATP translocase 2, ADT2_HUMAN, ANT 2, ANT, ATP carrier protein 3, ADP ATP carrier protein heart/skeletal muscle isoform T3, ADP/ATP translocase 3, ADT3_HUMAN, ANT3, ATP carrier protein 4, ADP ATP carrier protein heart/skeletal muscle isoform T4, ADP/ATP translocase 4, ADT4_HUMAN, ANT 4,ANT4.
Background: Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
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