HAO1 抗体 (AA 261-370)
Quick Overview for HAO1 抗体 (AA 261-370) (ABIN1387800)
抗原
See all HAO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-370
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GOX/HAO1
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亚型
- IgG
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anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) (AA 113-369) antibody
HAO1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) antibodyHAO1 适用: 小鼠, 大鼠 WB, IHC (p), IF 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) (AA 1-370) antibodyHAO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) (AA 161-273) antibodyHAO1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) antibodyHAO1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) antibodyHAO1 适用: 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal Mix unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) antibodyHAO1 适用: 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) (AA 1-370) antibodyHAO1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) (AA 251-300) antibodyHAO1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马, 猴, 兔, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) antibodyHAO1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
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别名
- HAO1
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背景
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Synonyms: Glycolate oxidase, GOX, GOX1, HAO1, HAOX1, HAOX1_HUMAN, Hydroxyacid oxidase 1, MGC142225, MGC142227, OTTHUMP00000030231, S 2 hydroxy acid oxidase.
Background: GOX is a 370 amino acid protein that is expressed in liver and pancreas. HAO1 is localized to peroxisomes and aids in organic acid metabolism via 2-hydroxyacid oxidase activity. 2-hydroxyacid oxidases, such as HAO1, are enzymes that require a flavin cofactor to oxidize 2-hydroxyacids to 2-ketoacids while reducing oxygen to hydrogen peroxide. HAO1 prefenentially oxidizes the substrate glycolate and also oxidizes other substrates, including 2-hydroxy fatty acids as well as L-?hydroxy acids of moderately short chain lengths. The oxidation of glycolate yields glyoxylate which is utilized for peroxisomal synthesis of glycine. HAO1 is also able to convert glyoxylate to oxalate. HAO1 is thought to play a role in the pathophysiology of hyperoxaluria type 1, which is caused by defects in AGXT, a peroxisomal enzyme, leading to accumulation of glyoxylate. Hyperoxaluria type 1 is characterized by an accumulation of oxalate that is thought to lead to precipitates of calcium oxalate in kidneys which can be fatal.
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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