GLIS2 抗体 (AA 271-350)
Quick Overview for GLIS2 抗体 (AA 271-350) (ABIN1387778)
抗原
See all GLIS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-350
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GLIS2
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亚型
- IgG
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anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 332-505) antibody
GLIS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (N-Term) antibodyGLIS2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 83-132) antibodyGLIS2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 183-232) antibodyGLIS2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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别名
- GLIS2
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背景
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Synonyms: NPHP7, NKL, GLI kruppel family member 2, GLI similar 2, GLI-similar 2, GLIS 2, GLIS family zinc finger 2, glis2, GLIS2_HUMAN, Kruppel like zinc finger protein GLIS2, Neuronal Krueppel-like protein, Tax helper protein, THP, Zinc finger protein GLI2, Zinc finger protein GLIS2.
Background: GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by a??-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Kr??ppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.
抗原
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