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CELSR3 抗体 (AA 1601-1700)

This anti-CELSR3 antibody is a 兔 多克隆 antibody detecting CELSR3 in ELISA, IHC (p), ICC, IF (cc), IF (p) 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1387763
发货至: 中国

Quick Overview for CELSR3 抗体 (AA 1601-1700) (ABIN1387763)

抗原

See all CELSR3 抗体
CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))

适用

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宿主

  • 26
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克隆类型

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多克隆

标记

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This CELSR3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 5
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    AA 1601-1700

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Flamingo homolog 1

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Su, Zhang, Gan, Jiang, Xiao, Zou, Li, Jiang: "Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).

  • 抗原

    CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))

    别名

    CELSR3/Flamingo homolog 1

    背景

    Synonyms: Cadherin EGF LAG seven-pass G-type receptor 3, Cadherin family member 11, CDHF11, CELR3_HUMAN, CELSR3, EGF-like protein 1, EGFL1, Epidermal growth factor-like protein 1, Flamingo, Flamingo homolog 1, FMI1, HFMI1, MEGF2, Multiple EGF-like domains protein 2, Multiple epidermal growth factor-like domains protein 2.

    Background: Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.

    基因ID

    1951

    UniProt

    Q9NYQ7
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