ADAM12 抗体 (AA 251-350)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for ADAM12 抗体 (AA 251-350) (ABIN1387748)
抗原
See all ADAM12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-350
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Dog,Cow,Pig,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human ADAM12/MLTN
-
亚型
- IgG
-
-
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 589-738) antibody
ADAM12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 513-767) antibodyADAM12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) antibodyADAM12 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 208-304) antibodyADAM12 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 730-909) antibodyADAM12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) antibodyVerified ADAM12 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 201-300) antibodyADAM12 适用: 人, 小鼠 ELISA, WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) antibodyADAM12 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 208-304) antibodyADAM12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 12 (ADAM12) (AA 1-737) antibodyADAM12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
-
: "HIF-1α, NOTCH1, ADAM12, and HB-EGF are overexpressed in mucoepidermoid carcinoma." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 127, Issue 1, pp. e8-e17, (2019) (PubMed).
-
: "HIF-1α, NOTCH1, ADAM12, and HB-EGF are overexpressed in mucoepidermoid carcinoma." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 127, Issue 1, pp. e8-e17, (2019) (PubMed).
-
- ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))
-
别名
- ADAM12
-
背景
-
Synonyms: MLTN, A disintegrin and metalloproteinase domain 12, A disintegrin and metalloproteinase domain 12, ADA12_HUMAN, ADAM 12, ADAM metallopeptidase domain 12, ADAM12, Disintegrin and metalloproteinase domain-containing protein 12, MCMP, MCMPMltna, MCMPMltna, Meltrin alpha, Meltrin-alpha, MLTN, MLTNA, OTTHUMP00000046766.
Background: ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).
-
途径
- EGFR Signaling Pathway
抗原
-
