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Musashi 1/2 (AA 66-150) 抗体

适用: 小鼠, 大鼠 IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387744
发货至: 中国
  • 抗原
    Musashi 1/2
    抗原表位
    AA 66-150
    适用
    小鼠, 大鼠
    宿主
    克隆类型
    多克隆
    应用范围
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Musashi 1
    亚型
    IgG
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Musashi 1/2
    背景

    Synonyms: Msi 1, Msi1, Msi-1, MSI1H_HUMAN, Musashi homolog 1, Musashi-1, Musashi1, Musashi 1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1, Msi 2, Msi2, Msi-2, MSI2H_HUMAN, Musashi homolog 2, Musashi-2, Musashi2, Musashi 2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2.

    Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.

    基因ID
    4440, 124540
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